Retin-A (tretinoin) is the original and, according to many, still the best topical cream to address a range of skin concerns—most notably acne, but also works to reduce fine wrinkles, reverse sun damage, and improve and even out skin tone. Retin-A belongs to a group of medications known as topical retinoids that are derived from vitamin A. It is available by prescription in many strengths in both gel and cream forms.

How it works ?

When you first begin using Retin-A, your skin may actually look worse. Expect some redness, dryness, and itching in the first weeks. You’ll apply a pea-size amount to clean skin at bedtime.“Most of my patients take about six weeks to several months to get used to using Retin-A and see changes in the skin, so we recommend a slow approach,” Just use the Retin-A at night and the Vitamin C in the morning—never together and alsothe addition of a glycolic lotion and sunscreen to your morning regimen would further add to your skin rejuvenation.”

Results:It can take months to see improvement in acne and hyperpigmentation, so if the Retin-A is used for acne, you may need additional medications to speed up the process,”


When you first apply Retin-A, you might feel a stinging, warm, or burning sensation, and your skin may get red. This is normal and should go away after a few minutes. If you have a burning sensation that’s beyond your comfort level or lasts longer than a few minutes, stop using the medication and ask your doctor if you should switch to a lower dose.Retin-A also causes sun sensitivity. Use a sunscreen of SPF 30 or higher and reduce sun exposure (including tanning beds) while taking this medication. Use a gentle, non-medicated cleanser and a good moisturizer to help to soothe any tight, dry skin.

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